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Image Search Results
Journal: Biomolecules
Article Title: Catalpol Ameliorates Insulin Sensitivity and Mitochondrial Respiration in Skeletal Muscle of Type-2 Diabetic Mice Through Insulin Signaling Pathway and AMPK/SIRT1/PGC-1α/PPAR-γ Activation
doi: 10.3390/biom10101360
Figure Lengend Snippet: Effect of catalpol on state-3/stae-4 respiration, oxygen consumption rate (OCR) and respiratory exchange rate (RCR) ( A ) Representative trace of oxygen consumption shown by relative fluorescent units (RFU) over time between 0 and 10 min. ( B ) Oxygen onsumptionrate of isolated mitochondria from skeletal muscle. The slopes of the oxygen consumption curves were measured between 0 and 10 min; ( C ) Respiratory Control Ratio (RCR) was calculated as the ratio of State 3 versus State 4 respiration slope. NORM: Normal control; DIA: Diabetic control; CAT_200: Catalpol (200 mg/kg; p.o.); MET_200: Metformin (200 mg/kg, p.o.). Data represents mean ± SEM ( n = 3 per group as pooled sample). # p < 0.05 and ## p < 0.01 vs. NORM; * p < 0.05 and ** p < 0.01 vs. DIA.
Article Snippet: Oxygen consumption rate was measured using
Techniques: Isolation, Control